国际肿瘤学杂志

国际肿瘤学杂志 ›› 2019, Vol. 46 ›› Issue (9): 536-539.doi: 10.3760/cma.j.issn.1673-422X.2019.09.005

• 综述 • 上一篇    下一篇

果糖代谢与肿瘤

张志萍，祁小飞   

  1. 苏州大学附属第一医院血液内科 江苏省血液研究所 卫生部血栓与止血重点实验室 血液学协同创新中心 苏州大学造血干细胞移植研究所215006
  • 收稿日期:2019-07-22 出版日期:2019-09-08 发布日期:2019-09-08
  • 通讯作者: 祁小飞 E-mail:qixiaofei@suda.edu.cn

Fructose metabolism and tumors

Zhang Zhiping, Qi Xiaofei   

  1. Department of Hematology, First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, Collaborative Innovation Center of Hematology, Institute of Blood and Marrow Transplantation, Soochow University, Suzhou 215006, China
  • Received:2019-07-22 Online:2019-09-08 Published:2019-09-08
  • Contact: Qi Xiaofei E-mail:qixiaofei@suda.edu.cn

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摘要： 糖类摄取增加可视为多种肿瘤的危险因素，包括乳腺癌、肺癌、子宫内膜癌、卵巢癌、胆囊癌、胰腺癌等。果糖可通过多种机制促进肿瘤形成及进展，导致不良预后及化疗耐药的增加。限制果糖摄取可降低肿瘤发生风险、延缓肿瘤进展、改善耐药性，起到辅助治疗作用。

关键词: 肿瘤, 果糖, 代谢

Abstract: Increasing sugar intake can be considered as a risk factor for some tumors, such as breast cancer, lung cancer, endometrial cancer, ovarian cancer, gallbladder cancer, pancreatic cancer, etc. Fructose can promote tumor formation and progression by several mechanisms, resulting in poor prognosis and increased chemotherapy resistance. Limitation of fructose consumption can reduce the risk of tumor, delay tumor progression and improve drug resistance, playing an auxiliary role in tumor treatment.

Key words: Neoplasms, Fructose, Metabolism