国际肿瘤学杂志 ›› 2017, Vol. 44 ›› Issue (8): 608-611.doi: 10.3760/cma.j.issn.1673-422X.2017.08.013

• 综述 • 上一篇    下一篇

早期乳腺癌保乳术后全乳放疗替代模式

张群, 李多杰   

  1. 233000蚌埠医学院第一附属医院放疗科
  • 出版日期:2017-08-08 发布日期:2017-07-21
  • 通讯作者: 李多杰,Email: liduojie@163.com E-mail: liduojie@163.com
  • 基金资助:

    安徽省“十二五”临床重点专科建设计划(01Z33);蚌埠医学院2016年度研究生科研创新计划(byycx1651)

Alternative mode of whole-breast radiotherapy after breast-conserving surgery in early-stage breast cancer

Zhang Qun, Li Duojie   

  1. Department of Radiotherapy, First Affiliated Hospital of Bengbu Medical College, Bengbu 233000, China
  • Online:2017-08-08 Published:2017-07-21
  • Contact: Li Duojie, Email: liduojie@163.com E-mail: liduojie@163.com
  • Supported by:

    Anhui Provincial Key Clinical Specialty Construction Fund of 12th Five-Year Plan (01Z33); 2016 Graduate Innovation Program of Bengbu Medical College (byycx1651)

摘要: 全乳房照射已被用于降低早期乳腺癌保乳术后同侧乳腺肿瘤复发的风险,并且多项随机临床试验和荟萃分析已经证明这一放疗模式安全有效,但随着放疗技术的进步以及患者生存期的延长,这种标准治疗模式目前也面临着一些挑战,其替代模式受到了越来越多的关注。其中部分乳腺照射、全乳大分割放疗、省略放疗针对不同的乳腺癌患者,疗效与全乳腺常规照射相当,且降低了不良反应,同时缩短了治疗时程,减轻了患者负担,值得在临床推广应用。

关键词: 乳腺肿瘤, 放射疗法, 保乳手术

Abstract: Wholebreast irradiation has been used to reduce the risk of ipsilateral breast tumor recurrence after breastconserving surgery for early breast cancer. A number of randomized clinical trials and metaanalyses have demonstrated the effectiveness and safety of wholebreast irradiation. With the progress of radiotherapy and the survival extented of patients, this standard treatment model is facing some challenges for different breast cancer groups, and its alternative model has been paid  more attention at the same time. The efficacy of partial breast irradiation, hypofactionated whole breast irradiation and the omission of breast RT are equivalent to wholebreast irradiation, while the side effects are reduced. In the same time, they shorten the treatment time of patient and reduce the burden on the patient, which is worth for popularization and application in clinic.

Key words: Breast neoplasms, Radiotherapy, Breast-conserving surgery