国际肿瘤学杂志 ›› 2015, Vol. 42 ›› Issue (2): 141-143.doi: 10.3760/cma.j.issn.1673-422X.2015.02.016

• 综述 • 上一篇    下一篇

乳腺癌转移相关机制

钟晶敏,曾亮   

  1. 410013长沙,湖南省肿瘤医院暨中南大学湘雅医学院附属肿瘤医院病理科
  • 出版日期:2015-02-08 发布日期:2015-02-02
  • 通讯作者: 曾亮 E-mail:zlxx03@qq.com
  • 基金资助:

    湖南省科技计划(2014FJ6090)

Metastatic mechanisms of breast cancer

Zhong Jingmin, Zeng Liang   

  1. Department of Pathology, Hunan Cancer Hospital &  Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha 410013, China
  • Online:2015-02-08 Published:2015-02-02
  • Contact: Zeng Liang E-mail:zlxx03@qq.com

摘要: 乳腺癌在女性中有着高发病率和死亡率。虽然目前针对乳腺癌有了多种治疗方法,但是乳腺癌的转移仍是一个棘手的医学问题。目前,乳腺癌相关转移机制主要涉及上皮间质转化、细胞外基质的溶解、循环肿瘤细胞或播散性肿瘤细胞、肿瘤血管和肿瘤微环境等。乳腺癌相关转移机制的明确对预测和治疗乳腺癌转移有一定的指导意义。

关键词: 乳腺肿瘤, 肿瘤转移

Abstract: Breast neoplasm shows high rate of incidence and mortality among females. Although there are a variety of treatments for breast neoplasm, breast neoplasm metastasis is still an intractable medical problem. At present, the related mechanisms of breast neoplasm metastasis are as follows: epithelialmesenchymal transition, dissolution of extracellular matrix, circulating tumor cells or disseminated tumor cells, tumor vessels and tumor microenvironment. Making clear of the related mechanisms of breast neoplasm metastasis has certain guiding significance for the prediction and treatmence of breast neoplasm metastasis.

Key words: Breast neoplasms, Neoplasm metastasis