肿瘤休眠模型研究进展

doi:10.3760/cma.j.issn.1673-422X.2014.08.002

国际肿瘤学杂志 ›› 2014, Vol. 41 ›› Issue (8): 564-567.doi: 10.3760/cma.j.issn.1673-422X.2014.08.002

肿瘤休眠模型研究进展

朱梦晗,冯炜炜

200011上海，复旦大学附属妇产科医院妇科

收稿日期:2014-02-17 修回日期:2014-03-26 出版日期:2014-08-15 发布日期:2014-08-14
通讯作者: 冯炜炜，E-mail:jingsakura@gmail.com E-mail:jingsakura@gmail.com
基金资助:
国家自然科学基金（30973185）

Progression of tumor dormancy models

Zhu Menghan, Feng Weiwei

Department of Gynecology, Affiliated Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China

Received:2014-02-17 Revised:2014-03-26 Online:2014-08-15 Published:2014-08-14
Contact: Feng Weiwei E-mail:jingsakura@gmail.com

摘要/Abstract

摘要： 肿瘤休眠是指肿瘤细胞在人体内长期存在而没有明显生长的一种状态，休眠细胞是肿瘤复发和远处转移的根源之一。肿瘤休眠的确切机制仍不清楚。利用肿瘤细胞移植和体外培养，结合分子细胞学与分子生物学技术，建立肿瘤休眠复发的动物体内模型和体外模型，为进一步研究肿瘤休眠机制、探索肿瘤治疗新方案提供了平台。

关键词: 肿瘤, 实验性, 模型, 动物, 休眠期

Abstract: Tumor dormancy is a state that tumor cells longterm exist in human body, without obvious growth. Dormant cell is one of the origins of tumor recurrence or metastasis. The exact mechanism of tumor dormancy is still unclear. Combined with cellular and molecular biological techniques, tumor cell transplantation and culture in vitro can establish experimental tumor dormancyrecurrence models. These in vivo and in vitro models can be used to investigate mechanisms of tumor dormancy and to explore novel treatments.

Key words: Neoplasms, experimental, Models, animal, Dormancy period

朱梦晗,冯炜炜. 肿瘤休眠模型研究进展[J]. 国际肿瘤学杂志, 2014, 41(8): 564-567.

Zhu Menghan, Feng Weiwei. Progression of tumor dormancy models[J]. Journal of International Oncology, 2014, 41(8): 564-567.

参考文献

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肿瘤休眠模型研究进展

Progression of tumor dormancy models

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