国际肿瘤学杂志

国际肿瘤学杂志 ›› 2016, Vol. 43 ›› Issue (4): 289-292.doi: 10.3760/cma.j.issn.1673422X.2016.04.013

• 综述 • 上一篇    下一篇

活化的激酶C受体1与实体肿瘤

田广伟,李楠,辛彦   

  1. 110001 沈阳，中国医科大学附属第一医院肿瘤研究所胃肠肿瘤病理研究室 普通外科研究所肿瘤病理研究室
  • 出版日期:2016-04-08 发布日期:2016-03-02
  • 通讯作者: 辛彦，Email: yxin@mail.cmu.edu.cn E-mail:yxin@mail.cmu.edu.cn

Receptor of activated Ckinase 1 and solid tumors

Tian Guangwei, Li Nan, Xin Yan   

  1. Gastrointestinal OncoPathology Laboratory of Cancer Institute, Department of OncoPathology of General Surgery Institute, First Hospital of China Medical University, Shenyang 110001, China
  • Online:2016-04-08 Published:2016-03-02
  • Contact: Xin Yan E-mail:yxin@mail.cmu.edu.cn

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被引次数

1

摘要： 活化的激酶C受体1（RACK1）在多种肿瘤中有不同表达，因其含有的7个WD重复序列可与多种分子相互结合，RACK1除了可以激活蛋白激酶C，还在许多肿瘤相关信号通路中发挥作用。随着研究的不断深入，RACK1有望在肿瘤诊断、治疗以及预后等多方面发挥积极作用。

关键词: 肿瘤, 活化的激酶C受体1

Abstract: Receptor of activated Ckinase 1 (RACK1) shows different expression in various tumors, because its seven WD repeating sequences can combine with a variety of molecules. In addition to activating protein kinases C, RACK1 still plays a role in many tumorrelated signaling pathways. With the deepening of research, RACK1 is expected to play an active role in cancer diagnosis, treatment and prognosis.

Key words: Neoplasms, Receptor of activated Ckinase 1