NUF2与肿瘤预后

doi:10.3760/cma.j.cn371439-20211025-00027

国际肿瘤学杂志 ›› 2022, Vol. 49 ›› Issue (3): 164-167.doi: 10.3760/cma.j.cn371439-20211025-00027

NUF2与肿瘤预后

任梦¹, 杨璐², 赵晓婷¹, 岳文涛¹()

¹首都医科大学附属北京妇产医院北京妇幼保健院中心实验室,北京 100026
²北京亦庄国际蛋白药物技术有限公司,北京 100023

收稿日期:2021-10-25 修回日期:2021-11-10 出版日期:2022-03-08 发布日期:2022-03-22
通讯作者: 岳文涛 E-mail:yuewt@ccmu.edu.cn
基金资助:
北京市科技计划(Z181100001718193)

NUF2 and tumor prognosis

Ren Meng¹, Yang Lu², Zhao Xiaoting¹, Yue Wentao¹()

¹Central Laboratory, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing 100026, China
²Beijing Etinpro Technologies Co.Ltd, Beijing 100023, China

Received:2021-10-25 Revised:2021-11-10 Online:2022-03-08 Published:2022-03-22
Contact: Yue Wentao E-mail:yuewt@ccmu.edu.cn
Supported by:
Science & Technology Commission of Beijing Municipal of China(Z181100001718193)

摘要/Abstract

摘要：

NUF2负责动粒-微管的附着,在细胞有丝分裂期间姐妹染色单体的正确分离中起关键作用。NUF2在肝细胞癌、胰腺癌、食管癌、非小细胞肺癌、乳腺癌等多种肿瘤组织及细胞中高表达,可作为预后评估的有效标志物。进一步阐述NUF2与肿瘤预后的关系,将为NUF2应用于临床肿瘤预后判断提供帮助。

关键词: 肿瘤, 预后, NUF2

Abstract:

NUF2 is responsible for the attachment of kinetochore-microtubules and proper chromosome segregation during mitosis. NUF2 is highly expressed in hepatocellular carcinoma, pancreatic cancer, esophageal cancer, non-small cell lung cancer, breast cancer and other tumor tissues and cells, and can be used as prognostic markers. Further clarifying the relationship between NUF2 and tumor prognosis can provide help for the application of NUF2 in prognostic assessment of cancers.

Key words: Neoplasms, Prognosis, NUF2

任梦, 杨璐, 赵晓婷, 岳文涛. NUF2与肿瘤预后[J]. 国际肿瘤学杂志, 2022, 49(3): 164-167.

Ren Meng, Yang Lu, Zhao Xiaoting, Yue Wentao. NUF2 and tumor prognosis[J]. Journal of International Oncology, 2022, 49(3): 164-167.

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NUF2与肿瘤预后

NUF2 and tumor prognosis

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