Journal of International Oncology ›› 2014, Vol. 41 ›› Issue (8): 608-611.doi: 10.3760/cma.j.issn.1673-422X.2014.08.016

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Expression and significance of human tissue kallikrein in ovarian cancer

Chu Fangbo, Chen Yingjian, Hu Chengjin   

  1. Graduate School of Liaoning Medical University, Jinzhou 121001, China
  • Received:2014-03-03 Revised:2014-04-05 Online:2014-08-15 Published:2014-08-14
  • Contact: Hu Chengjin E-mail:hcj90@263.net

Abstract: The human tissue kallikrein (KLK) gene family consists of 15 highly conservative serine proteases, which is the largest uninterrupted cluster of protease genes in the human genome. Several members of the family are expected to be markers for tumor diagnosis and prognosis. Studies find that the expressions of KLK2-11 and KLK13-15 are abnormal, and the majority of KLKs have potential diagnostic and prognostic values.

Key words: Ovarian neoplasms, Tumor markers, biological, Human tissue kallikrein