Journal of International Oncology ›› 2014, Vol. 41 ›› Issue (6): 401-404.

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MicroRNA and cancerassociated signal transduction pathways

Ye Zhennan, Xu Shanshui, Fang Xinggen.   

  1. Department of Neurosurgery, Affiliated Yijishan Hospital of Wannan Medical College, Wuhu 241000, China
  • Online:2014-06-08 Published:2014-05-08
  • Contact: Xu Shanshui E-mail:wyswxss66@126.com

Abstract: MicroRNA (miRNA), which is closely related to the occurrence and development of tumors, may act as oncogenes or tumor suppressor genes by regulating target genesrelated signal transduction pathways, such as epidermal growth factor receptor pathway, phosphatidylinositol 3kinaseprotein kinase B pathway and Ras signal transduction pathway. It is believed that miRNAs have broad application prospects in the treatment of tumors.

Key words: MicroRNAs, Neoplasms, Signal transduction