Anti-tumor mechanisms of oleanolic acid

doi:10.3760/cma.j.issn.1673-422X.2014.02.006

Abstract

Abstract: Oleanolic acid (OA), a pentacyclic triterpenoid, possesses a variety of pharmacological activities, such as hepatoprotective effect, antiinflammatory, enhancing immunity. Recently, many studies show that OA has inhibitory effects on the growth of many tumors and is a kind of potential antitumor drug. Its antitumor mechanisms mainly include regulating signaling pathway, arresting cell cycle, inducing apoptosis, antiangiogenesis, inhibiting tumor invasion and so on.

Key words: Oleanolic acid, Antineoplastic agents, Apoptosis

Huang Xuexiang, Yang Yu. Anti-tumor mechanisms of oleanolic acid[J]. Journal of International Oncology, 2014, 41(2): 96-99.

References

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