Tumor necrosis factor-related apoptosis inducing ligand and its receptors in hepatocellular carcinoma

Journal of International Oncology ›› 2013, Vol. 40 ›› Issue (8): 605-607.

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Tumor necrosis factor-related apoptosis inducing ligand and its receptors in hepatocellular carcinoma

XU Jian, LI Jing-Dong

Department of General Surgery,Institute of Hepatobiliary-Pancreatic-Intestinal Diseases, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China

Online:2013-08-08 Published:2013-08-15
Contact: Corresponding author：LI Jing-dong, E-mail: lijingdong358@126.com E-mail: lijingdong358@126.com

Abstract

Abstract: Tumor necrosis factor-related apoptosis inducing ligands (TRAIL) and its receptors can specifically express in hepatocellular carcinoma cells. TRAIL can specifically induce tumor cells apoptosis through death receptors (DRs); TRAIL combined radiation and chemotherapy can effectively overcome the TRAIL resistance of tumor cells, and promote the apoptosis of tumor cells, meanwhile the gene therapy of TRAIL on anti-tumor clinical treatment has been widely used.

Key words: TNF-related apoptosis-inducing ligand, Receptors, TNF-related apoptosis-inducing ligand, Liver neoplasms

XU Jian, LI Jing-Dong. Tumor necrosis factor-related apoptosis inducing ligand and its receptors in hepatocellular carcinoma[J]. Journal of International Oncology, 2013, 40(8): 605-607.

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Tumor necrosis factor-related apoptosis inducing ligand and its receptors in hepatocellular carcinoma

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