Journal of International Oncology ›› 2013, Vol. 40 ›› Issue (5): 392-395.

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Analysis of high risk factors of liver metastasis in patients with postoperative colorectal cancer

JIANG  Yue, WANG  A-Man, ZHANG  Jie, BAN  Li-Ying, ZHOU  Tao   

  1. Department of Oncology, Cangzhou Tegrated Traditional Chinese and Western Medicine Hospital of Hebei Province, Cangzhou 061001, China
  • Online:2013-05-08 Published:2013-05-15
  • Contact: Zhou Tao E-mail:zhoutao1967@163.com

Abstract: Objective To screen the risk factors of liver metastasis in patients with postoperative colorectal cancer and to set up a mathematic model. Methods  One hundred and sixty-eight patients received radical surgery were retrospectively analyzed. Logistics model regression was used to identify the risk factors and ROC test to complete a mathematic model. Results The 3 and 5-year incidence rate of liver metastasis was 25.0% and 33.3%, respectively. The risk factors of liver metastasis were lymph node metastasis (LNM), tumor invasive depth (TID), histological grading (G) and preoperative serum tumor markers (PSM). The mathematic model was: logit (P)=-0.931+0.973×LNM+0.302×TID+0.637×G+0.042×PSM. Conclusion The risk factors of liver metastasis were LNM, TID, G and PSM, and the mathematic model could be set up.

Key words: Colorectal neoplasms, Neoplasm metastasis, Liver, Risk factors