Journal of International Oncology ›› 2013, Vol. 40 ›› Issue (2): 120-122.

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Lung adenocarcinoma progression schema

YANG  Zhen-Yu, FAN  Zhi-Wen, ZHANG  Lei   

  1. Clinical Medical Specialty , Xiangya School of Medicine, Central South University, Changsha 410013, China
  • Online:2013-02-08 Published:2013-01-25
  • Contact: Corresponding author: ZHANG Lei, E-mail: chinaray728@gmail.com E-mail:chinaray728@gmail.com

Abstract: Lung adenocarcinoma is usually thought to follow a linear multistep progression schema, that is precancerous lesions progress to adenocarcinoma in situ, and progress to micro-invasive adenocarcinoma, eventually some lung adenocarcinoma happen diffusion. However, recent ?ndings reveal that this linear progression schema might not occur in all lung adenocarcinoma subtypes, and some subtypes show a kind of non-linear progression schema. The study of these two kinds of schemas can help for early detection of lung adenocarcinoma.

Key words: Lung neoplasms, DNA methylation, Etiology