Roles of the SoxC family in tumor development and its clinical significance

doi:10.3760/cma.j.cn371439-20220408-00079

Abstract

Abstract:

SoxC transcription factors are a group of important protein molecules involved in gene transcription, translation and expression, which can regulate gene expression by specifically binding to corresponding target genes or proteins. The SoxC gene family has unique molecular structure features. Its members Sox4, Sox11 and Sox12 are abnormally expressed in a variety of tumors, and can be used as diagnostic and prognostic markers for different tumors. Investigating the pathogenic mechanisms of the SoxC transcription factor family and their clinical significance can increase the evidence for SoxC as a therapeutic target for tumors.

Key words: SoxC transcription factors, Neoplasms, Transcription factors

Zhang Dandan, Lin Gaoren, Xiao Qian, Liu Ying. Roles of the SoxC family in tumor development and its clinical significance[J]. Journal of International Oncology, 2022, 49(7): 416-419.

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