Journal of International Oncology ›› 2017, Vol. 44 ›› Issue (5): 383-385.doi: 10.3760/cma.j.issn.1673422X.2017.05.015

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Research and application of NVPBEZ235 in lung cancer

Chai Xiaoyu, Xu Meng, Liu Xinmin   

  1. Department of Geriatrics, Peking University First Hospital, Beijing 100034, China
  • Online:2017-05-08 Published:2017-04-19
  • Contact: Liu Xinmin E-mail:lxm2128@163.com
  • Supported by:

    National Natural Science Foundation of China (81270114)

Abstract: NVPBEZ235 is a newly developed dual phosphatidyl linositol kinase 3kinase (PI3K) and mammalian target of rapamycin (mTOR) inhibitor. Studies have revealed that NVPBEZ235 combinate with other drugs were effective in the treatment of lung cancer. NVPBEZ235 might have a potential application value for the treatment of lung cancer of EGFR mutation subtype and KRAS mutation subtype.

Key words: Lung neoplasms, Mutation, NVP-BEZ235