Expression and mechanism of UCA1 in gastrointestinal tumors

doi:10.3760/cma.j.issn.1673422X.2017.02.017

Journal of International Oncology ›› 2017, Vol. 44 ›› Issue (2): 142-144.doi: 10.3760/cma.j.issn.1673422X.2017.02.017

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Expression and mechanism of UCA1 in gastrointestinal tumors

Zhao Yi, Yan Shanjun, Wang Qizhi

Department of Gastroenterology, First Affiliated Hospital of Bengbu Medical College, Bengbu 233000, China

Online:2017-02-08 Published:2017-01-04
Contact: Wang Qizhi E-mail:wangqz2004@sina.com

Abstract

Abstract: Urothelial carcinoma associated 1 (UCA1) is a kind of long noncoding RNA (lncRNA), which has no capacities for coding proteins. UCA1 overexpresses in diverse tumors, and plays a pivotal role in initiation and progression of tumors. Researches indicate that UCA1 may function as an oncogene in gastrointestinal tumors, such as gastric cancer, colorectal cancer and hepatocellular cancer, and participate in regulating cell proliferation, metastasis and chemo-resistance.

Key words: Gastrointestinal neoplasms, Long non-coding RNA, Urothelial carcinoma associated 1

ZHAO Yi, YAN Shan-Jun, WANG Qi-Zhi. Expression and mechanism of UCA1 in gastrointestinal tumors[J]. Journal of International Oncology, 2017, 44(2): 142-144.

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Expression and mechanism of UCA1 in gastrointestinal tumors

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