Clinical influencing factors of immunotherapy for non-small cell lung cancer

doi:10.3760/cma.j.cn371439-20210927-00149

Abstract

Abstract:

In the treatment of non-small cell lung cancer (NSCLC), immunotherapies represented by immune checkpoint inhibitors are developing rapidly. It is the premise of precise treatment to clarify the influencing factors of NSCLC immunotherapy. In the course of immunotherapy for advanced NSCLC, elderly patients can obtain specific effect from immunotherapy; male patients benefit more from monotherapy; when steroid hormones are used for related symptoms caused by tumors, they are poor prognostic factors for patients. The occurrence of immune-related adverse events is a favorable prognostic factor while driving gene mutations and the use of antibiotics will reduce the efficacy of immunotherapy.

Key words: Carcinoma, non-small cell lung, Prognosis, Anti-bacterial agents, Immune checkpoint inhibitor

Liu Chaoxing, Yan Xuebing, Yang Mengxue, Mao Haiyan, Tong Jiandong. Clinical influencing factors of immunotherapy for non-small cell lung cancer[J]. Journal of International Oncology, 2021, 48(12): 751-754.

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