Prognostic role and mechanisms of abnormal coagulation system in lymphoma

doi:10.3760/cma.j.cn371439-20200318-00094

Abstract

Abstract:

Lymphoma is the most common hematological malignancy, often accompanied by coagulation abnormalities. Coagulative dysfunction leads to thromboembolic and bleeding complications, which greatly increases mortality in patients with lymphoma. The mechanisms of abnormal coagulation system in lymphoma mainly include the direct coagulation mechanism of tumor cells secreting procoagulant factors and the indirect coagulation mechanism of tumor cells activating the procoagulant potential of host cells. Coagulative factors may be related to the prognosis of lymphoma.

Key words: Lymphoma, Blood coagulation disorders, Prognosis, Mechanism

Chai Yue, Dong Mei. Prognostic role and mechanisms of abnormal coagulation system in lymphoma[J]. Journal of International Oncology, 2020, 47(10): 637-640.

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