Journal of International Oncology ›› 2018, Vol. 45 ›› Issue (6): 355-357.doi: 10.3760/cma.j.issn.1673-422X.2018.06.008

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Role of microRNA-373 in tumor

Shen Kai, Shao Fang, Feng Tongbao, Qi Chunjian   

  1. Tumor Research Center, Changzhou Second People′s Hospital, Nanjing Medical University, Changzhou 213000, China
  • Received:2018-03-13 Online:2018-06-08 Published:2018-07-31
  • Contact: Qi Chunjian E-mail:qichunjian@njmu.edu.cn
  • Supported by:

    National Natural Science Foundation of China (31501942, 31601156)

Abstract: MicroRNAs are non-coding small RNAs that participate in the regulation of post transcriptional gene expression. MicroRNAs play the roles of inhibiting cancer or promoting cancer in different tumors. MicroRNA-373 is one of the members of the microRNA-520/373 family, which is involved in cancer anoxic response and DNA damage repair. MicroRNA-373 is abnormal expressed in breast cancer, glioma, lung cancer, prostate cancer and other tumors, which may play an important role in tumor development process, especially in tumor invasion and migration.

Key words: Neoplasms, MicroRNAs, Neoplasms metastasis, Gene expression regulation