Journal of International Oncology ›› 2014, Vol. 41 ›› Issue (7): 507-511.

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PET hypoxia imaging and progress of enhancing radiosensitivity in hypoxic tumor

 LUO  Zheng, ZHU  Hua, LIN  Xin-Feng, XIAO  Shao-Wen, YANG  Zhi   

  1. *Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, Key Laboratory of Carcinogenesis and Translational Research, Beijing 100142, China
  • Online:2014-08-04 Published:2014-08-04
  • Contact: Yang Zhi E-mail:pekyz@163.com

Abstract: Hypoxia is one of the most important factors influencing cancer therapy and clinical prognosis. With positron emission tomography (PET) widely adopted in clinical practice, the development and application of PET hypoxia imaging agents has been much popular in the field currently. PET hypoxia imaging can detect tumor hypoxia region noninvasively, which has important significance for optimizing cancer treatment decisions and improving the prognosis of cancer.

Key words: Neoplasms, Radionuclide imaging, Radiationsensitizing agents, Positronemission tomography