Abstract: Adoptive cellular immunotherapy (ACI) achieves the elimination and control of tumor by mobilizing the body's immune function. It also has targeted efficacy and mild untoward effects. Cytokine-induced killer cells and tumor-infiltrating lymphocytes have been widely used in clinic and have obtained preliminary efficacy. With the development and clinical application of the specific gene transfer of T cell, it will further increase the efficacy of immunotherapy. At present, improving cell culture technology and cell function and using with other treatment are the key links to improve the efficacy of ACI.

Key words: Neoplasms, Immunotherapy, Killer cells