Journal of International Oncology ›› 2012, Vol. 39 ›› Issue (8): 622-625.

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Postoperative radiotherapy and chemotherapy in cervical cancer

XIA  Yi, LI  Yun-Hai, ZHAO  Sen   

  1. Department of Radiation Oncology, Minhang Branch of Cancer Hospital, Fudan University, Shanghai 200240, China
  • Online:2012-08-29 Published:2012-08-29
  • Contact: LI Yun-hai, E-mail: liyunhai@csco.org.cn E-mail:liyunhai@csco.org.cn

Abstract: Local recurrence is more frequent in postoperative cervical cancer patients with high-risk factors. It is confirmed that adjuvant pelvic radiotherapy (RT) for the cervical cancer patients after surgery with high-risk factors can improve local control but can′t improve the overall survival. Researches show that concurrent chemo-radiotherapy (CCRT) can improve survival rates compared with radiotherapy, but the adverse effects such as leucopenia and gastrointestinal toxicity are observed frequently. Intensity-modulated radiation therapy (IMRT) has been developed to deliver a high radiation dose to an irregular target volume, with relative sparing of adjacent normal tissues. IMRT has excellent local tumor control and overall survival.

Key words: Uterine cervical neoplasms, Radiotherapy, Drug therapy