Abstract: In vivo, dendritic cells（DCs）are the most powerful antigenpresenting cells （APCs）. DCs based neoplasm immunotherapy has recently become the focus of research. DCs can be used not only as separate cell vaccine to mediate antitumor immunity, but can also be combined with cytokines, immune cells, and other methods in tumor immunotherapy. In animal models and clinical trials, DCbased immunotherapy as well as other tumor immunotherapy strategies have gained more significant progress.

Key words: Dendritic cells, Neoplasms, Immunity