Epithelial cell adhesion molecule and tumor

Journal of International Oncology ›› 2012, Vol. 39 ›› Issue (10): 751-754.

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Epithelial cell adhesion molecule and tumor

ZHANG Qi, ZHANG Hong-Tao, ZHANG Shu-Cai

Department of Oncology, Beijing Chest Hospital, Capital Medical University, Beijing 101149, China

Online:2012-10-31 Published:2012-10-31
Contact: ZHANG Shu-cai, E-mail:zhangshucai6304@yahoo.com.cn E-mail:zhangshucai6304@yahoo.com.cn

Abstract

Abstract: Epithelial cell adhesion molecules (EpCAMs) play an important role in the process of gene expression and regulation by combining with nuclear receptor. Aberrant expression of EpCAMs has been detected in different types of cancers, such as breast cancer, lung cancer, gastric cancer, and etc. The research of EpCAMs in circulating tumor cells enrichment, tumor pathogenesis and prognosis will be conducive to achieve new breakthroughs in cancer targeted therapy.

Key words: Neoplasms, Antibodies, Therapy, EpCAM

ZHANG Qi, ZHANG Hong-Tao, ZHANG Shu-Cai. Epithelial cell adhesion molecule and tumor[J]. Journal of International Oncology, 2012, 39(10): 751-754.

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Epithelial cell adhesion molecule and tumor

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