Journal of International Oncology ›› 2012, Vol. 39 ›› Issue (10): 748-751.

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Mesenchymal stem cells as carriers in cancer therapy

 LI  Si-Yu, ZHAO  Qing-Hua   

  1. Department of Orthopaedic Surgery, Shanghai First People′s Hospital, Shanghai Jiaotong University, Shanghai 200080, China
  • Online:2012-10-31 Published:2012-10-31
  • Contact: ZHAO Qing-hua, E-mail:sawboneszhao@163.com E-mail:sawboneszhao@163.com

Abstract: Mesenchymal stem cells(MSCs) can directly act on tumor cells to inhibit their growth, and could also migrate to the tissue lesions and tumor tissues to transfer and express many kinds of anti-cancer factors. Numerous researches have applied MSCs as carriers of drugs to induce apoptosis, inhibit differentiation of tumor cells and inhibit tumor angiogenesis, and have got outstanding antitumor results.

Key words: Neoplasms, Gene therapy, Mesenchymal stem cells