Journal of International Oncology ›› 2012, Vol. 39 ›› Issue (10): 729-731.

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microRNA and tumor angiogenesis

 XIAO  Lei, CHI  Yu-Long, DING  Wen-Yuan, LIU  Yun-Lai   

  1. First Student Troop, Third Military Medical University, Chongqing 400038, China
  • Online:2012-10-31 Published:2012-10-31
  • Contact: LIU Yun-lai, E-mail: fooljohn2010@hotmail.com E-mail:fooljohn2010@hotmail.com

Abstract: Angiogenesis plays an important role in the development process of tumor, and related microRNA(miRNA) in tumor cells can regulate tumor angiogenesis via the pathway of vascular endothelial growth factor(VEGF). Therefore, the further study of miRNA function will provide more effective targets to inhibit tumor angiogenesis, and provide more reliable basis for the clinical diagnosis and treatment of tumor. 

Key words: MicroRNAs, Vascular endothelial growth factor A, Neoplasms, Neovascularization