Journal of International Oncology ›› 2022, Vol. 49 ›› Issue (7): 430-435.doi: 10.3760/cma.j.cn371439-20220602-00082

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Research progress of maintenance therapy for cervical cancer

Peng Chen1,2, Xie Yintong3, Zhang Xin4, Xie Peng2,5()   

  1. 1. Department of Graduate, Shandong Frist Medical University and Shandong Academy of Medical Sciences, Jinan 250117, China
    2. Department of Gynecological Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan 250117, China
    3. Department of Medical Imaging, Linshu County Traditional Chinese Medicine Hospital of Shandong Province, Linyi 276700, China
    4. Department of Medical Imaging, Linyi Traditional Chinese Medicine Hospital, Shandong Province, Linyi 276000, China
    5. Department of Gynecology, Liaocheng People's Hospital of Shandong Province, Liaocheng 252000, China
  • Received:2022-06-02 Revised:2022-06-08 Online:2022-07-08 Published:2022-09-19
  • Contact: Xie Peng E-mail:xiepengro@126.com
  • Supported by:
    Healthy Science Development Plan of Shandong Province of China(202009030673);Shandong Cancer Hospital Project(2020-PYB22);Bethune Translational Research Foundation of Radiation Oncology(flzh202125);Shandong Medical Association Clinical Research Foundation(YXH2022ZX02151);Key Research and Development Plan of Shandong Province of China(2020RKC03013)

Abstract:

Cervical cancer is a common malignant tumor that threatens women's life and health. Among them, the prognosis of recurrent or advanced cervical cancer is poor, and such patients often receive surgical treatment, radiotherapy, chemotherapy, etc., which makes it more difficult to choose a treatment plan. Even after the most effective treatment methods, the treatment failure rate of advanced cervical cancer is still high. Thanks to the research progress of tumor cell signaling pathway-related targets and immunotherapy, especially immune checkpoint inhibitors, new breakthroughs have been made in cervical cancer maintenance therapy. Targeted maintenance therapy, immune maintenance therapy, and multi-drug combination maintenance therapy are currently popular areas of cervical cancer maintenance therapy.

Key words: Uterine cervical neoplasms, Recurrence, Neoplasm metastasis, Maintenance treatment