Application of non-coding RNAs in early diagnosis of colorectal cancer

doi:10.3760/cma.j.cn371439-20210119-00096

Abstract

Abstract:

Non-coding RNAs (ncRNAs) is a kind of RNA without protein coding function. A large number of studies in recent years have shown that the occurrence and development of colorectal cancer (CRC) are closely related to the aberrant expression of ncRNAs. ncRNAs can be used as non-invasive biomarkers for early diagnosis of CRC. We review the research progress of ncRNAs in early diagnosis of CRC, and summarize the potential clinical value of ncRNAs detection, which can provide a theoretical basis for improving the early diagnosis rate of CRC.

Key words: Colorectal neoplasms, Non-coding RNA

Wang Pei, Cui Manli, Zhang Mingxin. Application of non-coding RNAs in early diagnosis of colorectal cancer[J]. Journal of International Oncology, 2021, 48(8): 502-506.

References 38

[1]	王裴, 张明鑫, 张超, 等. 粪便DNA甲基化检测在结直肠癌早期诊断中的研究进展[J]. 现代肿瘤医学, 2015,23(6):874-880. DOI: 10.3969/j.issn.1672-4992.2015.06.42. doi: 10.3969/j.issn.1672-4992.2015.06.42
[2]	Nikolaou S, Qiu S, Fiorentino F, et al. Systematic review of blood diagnostic markers in colorectal cancer[J]. Tech Coloproctol, 2018,22(7):481-498. DOI: 10.1007/s10151-018-1820-3. doi: 10.1007/s10151-018-1820-3 pmid: 30022330
[3]	Slaby O. Non-coding RNAs as biomarkers for colorectal cancer scree-ning and early detection[J]. Adv Exp Med Biol, 2016,937:153-170. DOI: 10.1007/978-3-319-42059-2_8. doi: 10.1007/978-3-319-42059-2_8
[4]	Toiyama Y, Okugawa Y, Tanaka K, et al. A panel of methylated microRNA biomarkers for identifying high-risk patients with ulcerative colitis-associated colorectal cancer[J]. Gastroenterology, 2017, 153(6): 1634-1646.e8. DOI: 10.1053/j.gastro.2017.08.037. doi: S0016-5085(17)36070-5 pmid: 28847750
[5]	Michael MZ, O'Connor SM, van Holst Pellekaan NG, et al. Reduced accumulation of specific microRNAs in colorectal neoplasia[J]. Mol Cancer Res, 2003,1(12):882-891. pmid: 14573789
[6]	Karimi L, Mansoori B, Shanebandi D, et al. Function of microRNA-143 in different signal pathways in cancer: new insights into cancer therapy[J]. Biomed Pharmacother, 2017,91:121-131. DOI: 10.1016/j.Biopha.2017.04.060. doi: S0753-3322(17)30698-4 pmid: 28448866
[7]	Liu T, Liu D, Guan S, et al. Diagnostic role of circulating miR-21 in colorectal cancer: a update meta-analysis[J]. Ann Med, 2021,53(1):87-102. DOI: 10.1080/07853890.2020.1828617. doi: 10.1080/07853890.2020.1828617
[8]	Sabry D, El-Deek SEM, Maher M, et al. Role of miRNA-210, miRNA-21 and miRNA-126 as diagnostic biomarkers in colorectal carcinoma: impact of HIF-1α-VEGF signaling pathway[J]. Mol Cell Biochem, 2019,454(1-2):177-189. DOI: 10.1007/s11010-018-3462-1. doi: 10.1007/s11010-018-3462-1 pmid: 30357530
[9]	Sheng WZ, Chen YS, Tu CT, et al. MicroRNA-21 promotes phosphatase gene and protein kinase B/phosphatidylinositol 3-kinase expression in colorectal cancer[J]. World J Gastroenterol, 2016,22(24):5532-5539. DOI: 10.3748/wjg.v22.i24.5532. doi: 10.3748/wjg.v22.i24.5532
[10]	Imaoka H, Toiyama Y, Fujikawa H, et al. Circulating microRNA-1290 as a novel diagnostic and prognostic biomarker in human colo-rectal cancer[J]. Ann Oncol, 2016,27(10):1879-1886. DOI: 10.1093/annonc/mdw279. doi: 10.1093/annonc/mdw279 pmid: 27502702
[11]	赵高传, 陈卿奇, 庞莉, 等. miR-205及miR-221在结肠癌患者血清中的水平及其临床意义[J]. 国际肿瘤学杂志, 2019,46(9):526-530. DOI: 10.3760/cma.j.issn.1673-422X.2019.09.003. doi: 10.3760/cma.j.issn.1673-422X.2019.09.003
[12]	Zhu M, Huang Z, Zhu D, et al. A panel of microRNA signature in serum for colorectal cancer diagnosis[J]. Oncotarget, 2017,8(10):17081-17091. DOI: 10.18632/oncotarget.15059. doi: 10.18632/oncotarget.15059
[13]	Kanaan Z, Roberts H, Eichenberger MR, et al. A plasma micro-RNA panel for detection of colorectal adenomas: a step toward more precise screening for colorectal cancer[J]. Ann Surgery, 2013,258(3):400-408. DOI: 10.1097/SLA.0b013e3182a15bcc. doi: 10.1097/SLA.0b013e3182a15bcc
[14]	韦皓棠, 陈利生. 粪便miRNA检测在结直肠癌诊断中的价值[J]. 结直肠肛门外科, 2017,23(5):565-569. DOI: 1674-0491(2017)05-0565-05. doi: 1674-0491(2017)05-0565-05
[15]	Chang PY, Chen CC, Chang YS, et al. MicroRNA-223 and microRNA-92a in stool and plasma samples act as complementary biomarkers to increase colorectal cancer detection[J]. Oncotarget, 2016,7(9):10663-10675. DOI: 10.18632/oncotarget.7119. doi: 10.18632/oncotarget.7119
[16]	Ahmed FE, Ahmed NC, Vos PW, et al. Diagnostic microRNA markers to screen for sporadic human colon cancer in stool: Ⅰ. Proof of principle[J]. Cancer Genomics Proteomics, 2013,10(3):93-113.
[17]	Liu J, Li H, Zheng B, et al. Competitive endogenous RNA (ce-RNA) regulation network of lncRNA-miRNA-mRNA in colorectal carcinogenesis[J]. Dig Dis Sci, 2019,64(7):1868-1877. DOI: 10.1007/s10620-019-05506-9. doi: 10.1007/s10620-019-05506-9
[18]	Shuwen H, Qing Z, Yan Z, et al. Competitive endogenous RNA in colorectal cancer: a systematic review[J]. Gene, 2018,645:157-162. DOI: 10.1016/j.gene.2017.12.036. doi: S0378-1119(17)31089-2 pmid: 29273554
[19]	Xiao Z, Qu Z, Chen Z, et al. LncRNA HOTAIR is a prognostic biomarker for the proliferation and chemoresistance of colorectal cancer via miR-203a-3p-mediated Wnt/β-Catenin signaling pathway[J]. Cell Physiol Biochem, 2018,46(3):1275-1285. DOI: 10.1159/000489110. doi: 10.1159/000489110
[20]	Ismail DM, Shaker OG, Kandeil MA, et al. Gene expression of the circulating long oncoding RNA H19 and HOTAIR in Egyptian colo-rectal cancer patients[J]. Genet Test Mol Biomarkers, 2019,23(9):671-680. DOI: 10.1089/gtmb.2019.0066. doi: 10.1089/gtmb.2019.0066
[21]	Liu T, Zhang X, Gao S, et al. Exosomal long noncoding RNA CRNDE-h as a novel serum-based biomarker for diagnosis and prognosis of colorectal cancer[J]. Oncotarget, 2016,7(51):85551-85563. DOI: 10.18632/oncotarget.13465. doi: 10.18632/oncotarget.13465
[22]	Cheng Y, Wu J, Qin B, et al. CREB1-induced lncRNA LEF1-AS1 contributes to colorectal cancer progression via the miR-489/DIAPH1 axis[J]. Biochem Biophys Res Commun, 2020,526(3):678-684. DOI: 10.1016/j.bbrc.2020.03.153. doi: 10.1016/j.bbrc.2020.03.153
[23]	Shi Q, He Y, Zhang X, et al. Two novel long noncoding RNAs—RP11-296E3.2 and LEF1-AS1can—separately serve as diagnostic and prognostic bio-markers of metastasis in colorectal cancer[J]. Med Sci Monit, 2019,25:7042-7051. DOI: 10.12659/MSM.916314. doi: 10.12659/MSM.916314
[24]	Liu H, Ye D, Chen A, et al. A pilot study of new promising non-coding RNA diagnostic biomarkers for early-stage colorectal cancers[J]. Clin Chem Lab Med, 2019,57(7):1073-1083. DOI: 10.1515/cclm-2019-0052. doi: 10.1515/cclm-2019-0052
[25]	Xu W, Zhou G, Wang H, et al. Circulating lncRNA SNHG11 as a novel biomarker for early diagnosis and prognosis of colorectal cancer[J]. Int J Cancer, 2020,146(10):2901-2912. DOI: 10.1002/ijc.32747. doi: 10.1002/ijc.32747
[26]	Gharib E, Nazemalhosseini-Mojarad E, Baghdar K, et al. Identification of a stool long non-coding RNAs panel as a potential biomarker for early detection of colorectal cancer[J]. J Clin Lab Anal, 2020,23:e23601. DOI: 10.1002/jcla.23601. doi: 10.1002/jcla.23601
[27]	Hao S, Cong L, Qu R, et al. Emerging roles of circular RNAs in colorectal cancer[J]. Onco Targets Ther, 2019,12:4765-4777. DOI: 10.2147/OTT.S208235. doi: 10.2147/OTT.S208235
[28]	Bach DH, Lee SK, Sood AK. Circular RNAs in cancer[J]. Mol Ther Nucleic Acids, 2019,16:118-129. DOI: 10.1016/j.omtn.2019.02.005. doi: 10.1016/j.omtn.2019.02.005
[29]	Geng HH, Li R, Su YM, et al. The circular RNA Cdr1as promotes myocardial infarction by mediating the regulation of miR-7a on its target genes expression[J]. PLoS One, 2016,11(3):e0151753. DOI: 10.1371/journal.pone.0151753. doi: 10.1371/journal.pone.0151753
[30]	Zhang P, Zuo Z, Shang W, et al. Identification of differentially expressed circular RNAs in human colorectal cancer[J]. Tumour Biol, 2017,39(3):1010428317694546. DOI: 10.1177/1010428317694546. doi: 10.1177/1010428317694546
[31]	Hou J, Jiang W, Zhu L, et al. Circular RNAs and exosomes in cancer: a mysterious connection[J]. Clin Transl Oncol, 2018,20(9):1109-1116. DOI: 10.1007/s12094-018-1839-y. doi: 10.1007/s12094-018-1839-y pmid: 29536331
[32]	唐梦甜, 周菊梅, 廖前进, 等. 外泌体环状RNA在肿瘤微环境中的研究进展[J]. 生物化学与生物物理进展, 2021,48(2):135-146. DOI: 10.16476/j.pibb.2020.0191. doi: 10.16476/j.pibb.2020.0191
[33]	Wang Y, Mo Y, Gong Z, et al. Circular RNAs in human cancer[J]. Mol Cancer, 2017,16(1):25. DOI: 10.1186/s12943-017-0598-7. doi: 10.1186/s12943-017-0598-7
[34]	郝文静, 路丹. 环状RNA在肿瘤中的研究进展[J]. 肿瘤学杂志, 2019,25(3):243-246. DOI: 1671-170X(2019)03-0243-04. doi: 1671-170X(2019)03-0243-04
[35]	Yang N, Xu B, Kong P, et al. Hsa_circ_0002320: a novel clinical biomarker for colorectal cancer prognosis[J]. Medicine (Baltimore), 2020,99(28):e21224. DOI: 10.1097/MD.0000000000021224. doi: 10.1097/MD.0000000000021224
[36]	Zhang W, Yang S, Liu Y, et al. Hsa_circ_0007534 as a blood-based marker for the diagnosis of colorectal cancer and its prognostic value[J]. Int J Clin Exp Pathol, 2018,11(3):1399-1406.
[37]	Xing L, Xia M, Jiao X, et al. Hsa_circ_0004831 serves as a blood-based prognostic biomarker for colorectal cancer and its potentially circRNA-miRNA-mRNA regulatory network construction[J]. Cancer Cell Int, 2020,20(1):557. DOI: 10.1186/s12935-020-01651-8. doi: 10.1186/s12935-020-01651-8
[38]	Lin J, Cai D, Li W, et al. Plasma circular RNA panel acts as a novel diagnostic biomarker for colorectal cancer[J]. Clin Biochem, 2019,74:60-68. DOI: 10.1016/j.clinbiochem.2019.10.012. doi: 10.1016/j.clinbiochem.2019.10.012