Journal of International Oncology ›› 2020, Vol. 47 ›› Issue (6): 377-380.doi: 10.3760/cma.j.cn371439-20191216-00040

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New progress on diagnosis and treatment of anorectal malignant melanoma

Zhang Ruizhi, Chen Xin, Zhang Peng, Tao Kaixiong()   

  1. Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
  • Received:2019-12-16 Revised:2020-01-09 Online:2020-06-08 Published:2020-07-22
  • Contact: Tao Kaixiong E-mail:kaixiongtao@hust.edu.cn
  • Supported by:
    National Natural Science Foundation of China(81702386);National Natural Science Foundation of China(81874184);Huazhong University of Science and Technology Independent Innovation Research Fund(2017KFYXJJ230);Huazhong University of Science and Technology Independent Innovation Research Fund(2017KFYXJJ256);Xisike-Hansoh Cancer Research Fund(Y-HS2019-38)

Abstract:

Anorectal malignant melanoma (ARMM) is a rare malignant melanoma arising from mucosa in anorectal area. Symptoms and signs of ARMM are not specific, causing high misdiagnosis rate in this disease. Cornerstone treatment of ARMM is radical excision. Although more systematic therapy including target therapy and immunotherapy have been applied to ARMM, as the understanding of ARMM deepens. The overall prognosis of ARMM is still poor due to the lack of accurate clinical classification and staging standards.

Key words: Melanoma, Rectum, Anal canal, Diagnosis, Therapy