长非编码RNA GAS5在恶性肿瘤中的表达及作用

doi:10.3760/cma.j.issn.1673-422X.2016.06.012

国际肿瘤学杂志 ›› 2016, Vol. 43 ›› Issue (6): 445-447.doi: 10.3760/cma.j.issn.1673-422X.2016.06.012

长非编码RNA GAS5在恶性肿瘤中的表达及作用

胡以恒，张军

210006 南京医科大学附属南京医院（南京市第一医院）消化内科

收稿日期:2015-10-20 出版日期:2016-06-08 发布日期:2016-04-27
通讯作者: 张军 E-mail:zhangjun711028@126.com

Expression and role of long non-coding RNA GAS5 in human carcinomas

Hu Yiheng, Zhang Jun

Department of Gastroenterology, Affiliated Nanjing Hospital (Nanjing First Hospital), Nanjing Medical University, Nanjing 210006, China

Received:2015-10-20 Online:2016-06-08 Published:2016-04-27
Contact: Zhang Jun E-mail:zhangjun711028@126.com

摘要/Abstract

摘要： 生长停滞特异性转录因子5（GAS5）是一种常见的长非编码RNA，近年来研究发现GAS5在多种恶性肿瘤如乳腺癌、宫颈癌、肺癌、消化系肿瘤、泌尿系肿瘤等中表达下调，与肿瘤的发展、转移和预后密切相关，成为肿瘤研究的新热点。

关键词: 肿瘤, 生长停滞特异性转录因子5

Abstract: Growth arrest special 5 (GAS5) is a common long noncoding RNA (lncRNA). Recent studies find that lncRNA GAS5 is downregulated in various tumors, such as breast cancer, cervical cancer, lung cancer, gastrointestinal cancers and urologic cancers. GAS5 is closely related to the development, metastasis and prognosis of cancers, which becomes a new hotspot in cancer research.

Key words: Neoplasms, Growth arrest special 5

胡以恒，张军. 长非编码RNA GAS5在恶性肿瘤中的表达及作用[J]. 国际肿瘤学杂志, 2016, 43(6): 445-447.

Hu Yiheng, Zhang Jun. Expression and role of long non-coding RNA GAS5 in human carcinomas[J]. Journal of International Oncology, 2016, 43(6): 445-447.

参考文献

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长非编码RNA GAS5在恶性肿瘤中的表达及作用

Expression and role of long non-coding RNA GAS5 in human carcinomas

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