国际肿瘤学杂志 ›› 2016, Vol. 43 ›› Issue (6): 436-438.doi: 10.3760/cma.j.issn.1673-422X.2016.06.009

• 综述 • 上一篇    下一篇

HOXC基因在肿瘤中的表达与作用

李琳,贾秀红   

  1. 256603 滨州医学院附属医院儿科
  • 收稿日期:2015-07-25 出版日期:2016-06-08 发布日期:2016-04-27
  • 通讯作者: 贾秀红 E-mail:jiaxiuhong001@163.com
  • 基金资助:

    山东省自然科学基金(ZR2014HL032);山东省医药卫生科技发展计划(2014WS0183)

Expression and role of HOXC gene in tumor

Li Lin, Jia Xiuhong   

  1. Department of Pediatrics, Affiliated Hospital of Binzhou Medical University, Binzhou 256603, China
  • Received:2015-07-25 Online:2016-06-08 Published:2016-04-27
  • Contact: Jia Xiuhong E-mail:jiaxiuhong001@163.com
  • Supported by:

    Natural Science Foundation of Shandong Province of China (ZR2014HL032); Medical Science and Technique Program of Shandong Province of China (2014WS0183)

摘要: HOXC基因簇作为同源盒(HOX)基因家族的一员,在多种器官中均有表达,具有调控基因表达、细胞分化和机体形态发生的功能,而其功能的异常与白血病、乳腺癌、肾细胞癌、前列腺癌等肿瘤的预后密切相关。

关键词: 肿瘤, 基因, 同源盒, HOXC

Abstract: As a member of homeobox gene family, HOXC is expressed in many organs and can regulate gene expression, cell differentiation and morphogenesis. Abnormality of its function is closely related to the prognosis of leukemia, breast cancer, renal cell carcinoma, prostate cancer and so on.

Key words: Neoplasms, Genes, homeobox, HOXC