微小RNA-451在肿瘤中的研究进展

doi:10.3760/cma.j.issn.1673-422X.2014.12.003

摘要/Abstract

摘要： 微小RNA451(miR451)在胶质瘤、胃癌、结直肠癌和肝癌等多种肿瘤组织中明显低表达。上调 miR451的表达可以显著抑制肿瘤细胞的增殖、侵袭和转移，诱导肿瘤细胞凋亡，提高肿瘤细胞放、化疗敏感性等。

Abstract: MicroRNA451(miR451) is significantly lowly expressed in glioma, gastric cancer, colorectal cancer, liver cancer and other tumor tissues. Upregulation of miR451 can significantly inhibit tumor cell proliferation，invasion and metastasis as well as increasing tumor cell apoptosis and improving radiotherapy and chemotherapy sensitivity and other biological effects.

Key words: Neoplasms; , MicroRNAs

南阳, 钟跃. 微小RNA-451在肿瘤中的研究进展[J]. 国际肿瘤学杂志, 2014, 41(12): 887-890.

南Yang , ZHONG Yue. Research progress of miR-451 in tumor[J]. Journal of International Oncology, 2014, 41(12): 887-890.

参考文献

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