关键词: TNF相关凋亡诱导配体, 受体, TNF相关凋亡诱导配体, 肝肿瘤

Abstract: Tumor necrosis factor-related apoptosis inducing ligands (TRAIL) and its receptors can specifically express in hepatocellular carcinoma cells. TRAIL can specifically induce tumor cells apoptosis through death receptors (DRs); TRAIL combined radiation and chemotherapy can effectively overcome the TRAIL resistance of tumor cells, and promote the apoptosis of tumor cells, meanwhile the gene therapy of TRAIL on anti-tumor clinical treatment has been widely used.

Key words: TNF-related apoptosis-inducing ligand, Receptors, TNF-related apoptosis-inducing ligand, Liver neoplasms