国际肿瘤学杂志

国际肿瘤学杂志 ›› 2013, Vol. 40 ›› Issue (8): 584-586.

• 综述 • 上一篇    下一篇

肿瘤寡转移及其治疗策略

江雪, 严森祥, 徐秋一等   

  1. 310000 杭州,浙江大学医学院附属第一医院放疗科(江雪、严森祥、孙晓丽)，化疗科（徐秋一）
  • 出版日期:2013-08-08 发布日期:2013-08-15

Neoplasm oligometastasis and its therapeutic strategies

JIANG  Xue, YAN  Sen-Xiang, XU  Qiu-Yi, et al   

  1. Department of Radiation Oncology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310000, China
  • Online:2013-08-08 Published:2013-08-15

PDF

1693

被引次数

5

摘要： 寡转移是肿瘤转移过程中的一种中间状态，它是局限原发灶及广泛转移灶之间生物侵袭性较温和的阶段，是肿瘤转移灶数目少于5个的特殊时期。寡转移治疗的关键是放疗、手术和射频消融等局部治疗，同时兼顾预防远处转移。miR-200家族表达可以预测晚期肿瘤患者是否处于寡转移状态。认识寡转移并且熟悉寡转移的治疗方法可以改变传统治疗晚期肿瘤的方法，同时使部分晚期患者有潜在治愈的可能。

关键词: 肿瘤, 放射疗法, 外科手术, 寡转移

Abstract: The oligometastasic stage is an intermediate state with mild biological invasion, in which spread may be limited to specific organs and not occour polymetastases. The number of metastatic tumors is limited less than five. Local therapy such as radiotherapy, surgery and radiofrequency ablation for the relapsed sites could thus improve patient’s survival. The expression of miR-200 family characterizes oligometastasis(es). Correct understanding and familiarization with treatment of oligometastasis may change the traditional therapeutic strategy of advanced tumors，and some advanced cancer patients may achieve curable results.

Key words: Neoplasms, Radiotherapy, Surgical procedures, operative, Oligometastasis