国际肿瘤学杂志

国际肿瘤学杂志 ›› 2013, Vol. 40 ›› Issue (6): 443-447.

• 综述 • 上一篇    下一篇

18F-FDG PET-CT在鼻咽癌中的应用

苏艳霞, 郝俊芳   

  1. 250117 济南，山东省肿瘤医院放疗五科

  • 出版日期:2013-06-08 发布日期:2013-05-24
  • 通讯作者: 郝俊芳，E-mail: hao-j-f@163.com E-mail:hao-j-f@163.com

The application of 18F-FDG PET-CT in nasopharyngeal carcinoma

SU  Yan-Xia, HAO  Jun-Fang   

  1. The Fifth Clinical Department of Radiation Oncology, Shandong Tumor Hospital, Jinan  250117, China
  • Online:2013-06-08 Published:2013-05-24
  • Contact: HAO Jun-fang E-mail:hao-j-f@163.com

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摘要： 18F-氟脱氧葡萄糖（18F-FDG）PET-CT在鼻咽癌诊疗中的应用主要包括早期诊断、临床分期、靶区勾画、预测放疗敏感性、评价疗效及监测肿瘤残留与复发。但由于肿瘤细胞对18F-FDG的摄取受多因素的影响，假阳性和假阴性不可避免，因此需要开发特异性更高的示踪剂以提高诊疗的准确性，同时需要开展多中心研究，以明确标准摄取值(SUV)与放疗靶区勾画的关系。

关键词: 鼻咽肿瘤, 放射疗法, 正电子发射体层摄影-计算机断层摄影

Abstract: The application of 18F-FDG PET-CT in the diagnosis and treatment of nasopharyngeal carcinoma includes early diagnosis, clinical staging, contouring target volume, predicting the sensitivity of tumors to radiotherapy and effect evaluation, and monitoring the residual and recurrence. However, 18F-FDG uptake of tumor cells is under the influence of various factors, so false positive and false negative are unavoidable. Therefore it is need to develop more specific tracer agent in order to improve the accuracy of diagnosis and treatment, as well as to carry out multicenter clinical trial to identify the correlation of standardized uptake value （SUV） and radiation target volume.

Key words: Nasopharyngeal neoplasms, Radiotherapy, PET-CT