国际肿瘤学杂志 ›› 2013, Vol. 40 ›› Issue (2): 89-92.

• 综述 • 上一篇    下一篇

GOLPH2在肿瘤中的研究

李文智, 王翔, 陈刚   

  1. 201508上海 复旦大学附属金山医院泌尿外科(李文智、陈刚);复旦大学附属华山医院泌尿外科(王翔)
  • 出版日期:2013-02-08 发布日期:2013-01-25
  • 通讯作者: 陈刚,E-mail: uromail@sina.com E-mail:uromail@sina.com
  • 基金资助:

    国家自然科学基金(81170697)

Advances of GOLPH2 in tumors

LI  Wen-Zhi, WANG  Xiang, CHEN  Gang   

  1. Department of Urology,Jinshan Hospital, Fudan University, Shanghai 201508, China
  • Online:2013-02-08 Published:2013-01-25
  • Contact: Corresponding author: CHEN Gang, E-mail: uromail@sina.com E-mail:uromail@sina.com

摘要: 作为新型高尔基蛋白,GOLPH2的表达与维持高尔基体结构的完整性相关。作为癌蛋白,GOLPH2的表达与肿瘤细胞恶性生物学行为相关。GOLPH2在肿瘤发生和转移中的重要作用使之成为肿瘤诊断和治疗的新靶点。

关键词: GOLPH2, 肿瘤

Abstract: As a novel Golgi protein, GOLPH2 expression is associated with maintaining the structural integrity of the Golgi apparatus. As an oncoprotein, GOLPH2 expression is associated with malignant biological behavior of cancer cells. Important roles of GOLPH2 in the tumorigenesis and metastasis make it become a new target for tumor diagnosis and treatment.

Key words: Golgi phosphoprotein 2, Neoplasms