国际肿瘤学杂志 ›› 2013, Vol. 40 ›› Issue (1): 32-35.

• 综述 • 上一篇    下一篇

乳腺癌的新辅助全身治疗

江换钢, 周福祥   

  1. 430071武汉大学中南医院放化疗科
  • 出版日期:2013-01-08 发布日期:2013-01-15
  • 通讯作者: 周福祥,E-mail:happyzfx@sina.com E-mail:happyzfx@sina.com

Neoadjuvant systemic therapy for breast cancer

JIANG  Huan-Gang, ZHOU  Fu-Xiang   

  1. Department of Radiation and Chemotherapy, Zhongnan Hospital of Wuhan University, Wuhan 430071, China
  • Online:2013-01-08 Published:2013-01-15
  • Contact: Corresponding author: ZHOU Fu-xiang, E-mail: happyzfx@sina.com E-mail:happyzfx@sina.com

摘要: 乳腺癌新辅助全身治疗,是指对某些乳腺癌患者在术前给予其全身性的治疗。术前综合运用化疗、内分泌治疗和靶向治疗可起到降期和提高保乳手术率的独特作用。新辅助化疗已经成为局部晚期乳腺癌的标准治疗方式之一。新辅助条件下,对于特定患者使用芳香化酶抑制剂和曲妥珠单抗治疗的研究也取得了长足进步。

关键词: 乳腺肿瘤, 肿瘤辅助疗法, 药物疗法, 内分泌治疗, 靶向治疗

Abstract: Neoadjuvant systemic therapy for breast cancer patients means systemic treatments before operations. Combination chemotherapy, endocrine therapy and targeted therapy before operation can degrade the tumor staging and increase the breast-conserving rates. Neoadjuvant chemotherapy has been accepted as one of the standard therapies for patients with locally advanced breast cancers. In the neoadjuvant setting, the studies about the use of aromatase inhibitors and trastuzumab in selected patients have also made great progress.

Key words: Breast neoplasms, Neoadjuvant therapy, Drug therapy, Endocrine therapy, Targeted therapy