国际肿瘤学杂志

国际肿瘤学杂志 ›› 2013, Vol. 40 ›› Issue (1): 15-18.

• 综述 • 上一篇    下一篇

结肠癌转移相关基因1与肿瘤

李祯, 生秀杰   

  1. 510150广州医学院第三附属医院妇产科研究所  广东省普通高校生殖与遗传重点实验室
  • 出版日期:2013-01-08 发布日期:2013-01-15
  • 通讯作者: 生秀杰，E-mail: xjsheng@gzemail.cn E-mail:xjsheng@gzemail.cn

Metastasis-associated in colon cancer-1 and tumor

LI  Zhen, SHENG  Xiu-Jie   

  1. Department of Gynecology, the Third Affiliated Hospital of Guangzhou Medical College, Key Laboratory of Reproduction and Genetics of Guangdong Higher Education Institutes, Guangzhou 510150, China
  • Online:2013-01-08 Published:2013-01-15
  • Contact: Corresponding author: SHENG Xiu-jie, E-mail: xjsheng@gzemail.cn E-mail:xjsheng@gzemail.cn

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被引次数

1

摘要： 结肠癌转移相关基因1（MACC1）为新近发现的调节肿瘤生长和转移的基因，在多种恶性肿瘤中异常表达，其编码蛋白作为HGF-MET信号通路的一个关键调节因子，可明显增强肿瘤细胞的侵袭及转移能力。

关键词: 结肠癌转移相关基因1, 肿瘤, 肿瘤转移

Abstract: Metastasis-associated in colon cancer-1 (MACC1), a newly discovered gene which controls tumor growth and metastasis, abnormally expressed in a variety of malignant tumors. As a key regulator of HGF-MET signal pathway, its coding protein can obviously promote invasion and metastasis of tumor cells.

Key words: Metastasis-associated in colon cancer-1, Neoplasms, Neoplasm metastasis