国际肿瘤学杂志

国际肿瘤学杂志 ›› 2012, Vol. 39 ›› Issue (2): 117-120.

• 综述 • 上一篇    下一篇

不同体液中微小RNA在肿瘤诊断中的应用

谢子钧, 李子俊   

  1. 510080  广州， 广东省医学科学院 广东省人民医院消化内科
  • 出版日期:2012-02-08 发布日期:2012-01-18
  • 通讯作者: 李子俊，E-mail:zijunli2005@yahoo.com.cn E-mail:zijunli2005@yahoo.com.cn

The diagnostic applications of different body-fluid microRNAs in tumors

XIE  Zi-Jun, LI  Zi-Jun   

  1. Department of Gastroenterology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China
  • Online:2012-02-08 Published:2012-01-18
  • Contact: Corresponding author: LI Zi-jun, E-mail: zijunli2005@yahoo.com.cn E-mail:zijunli2005@yahoo.com.cn

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被引次数

2

摘要： 微小RNA（miRNA）与肿瘤的发生、发展及疾病的临床进程密切相关。检测人体各种体液中的miRNA如血液、胰液、痰液、唾液、尿液等的水平变化，对于肿瘤的分级、分期、早期诊断、预后预测和药物疗效评估均有一定作用。

关键词: font-family: 宋体, mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-bidi-font-family: 'Times New Roman', mso-font-kerning: 1.0pt, mso-hansi-font-family: 'Times New Roman', mso-ascii-font-family: 'Times New Roman'">微font-family: "Times New Roman", mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-fareast-font-family: 宋体, mso-font-kerning: 1.0pt">RNAsfont-family: 宋体, mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-bidi-font-family: 'Times New Roman', mso-font-kerning: 1.0pt, mso-ascii-font-family: 'Times New Roman'">, 体液, 肿瘤, 诊断

Abstract: MicroRNAs (miRNAs) are closely associated with cancer initiation, development and clinical progression. Detecting miRNA levels in different body fluids, such as sputum, pancreatic juice, saliva, urine, blood and so on, may play some roles in cancer classification, staging, early diagnosis, prognostic prediction and drug efficacy evaluation.

Key words: font-family: "Times New Roman", mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-fareast-font-family: 宋体, mso-font-kerning: 1.0pt">MicroRNAs, Body fluids, color: black, mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-fareast-font-family: 宋体, mso-bidi-font-family: 'Times New Roman', mso-font-kerning: 1.0pt, mso-bidi-font-size: 9.0pt">Neoplasmsfont-family: "Times New Roman", mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-fareast-font-family: 宋体, mso-font-kerning: 1.0pt">, Diagnosis