血小板在促进肿瘤进展中的作用

doi:10.3760/cma.j.issn.1673422X.2018.02.010

摘要/Abstract

摘要： 血小板在肿瘤进展中起重要的作用。血小板增多与较差的总生存期和预后相关。肿瘤细胞诱导的血小板活化和血小板诱导的肿瘤生长形成恶性扩增循环，在肿瘤细胞的增殖、转移、血管生成中发挥重要的作用。抗血小板的治疗策略可能会打破血小板肿瘤细胞扩增循环并在减少肿瘤的转移中发挥关键作用。

关键词: 血小板, 肿瘤

Abstract: Platelets play important roles in tumor progression. Increased platelets count is associated with poor overall survival and prognosis. Tumor cellinduced platelet activation and plateletinduced tumor growth form a malignant amplification loop which plays a crucial role in tumor cell proliferation, metastasis and angiogenesis. Antiplatelet therapy may break the platelettumor amplification loop and play a key role in reducing tumor metastasis.

Key words: Blood platelets, Neoplasms

陈罗军, 田景媛, 李娜, 宋启斌. 血小板在促进肿瘤进展中的作用[J]. 国际肿瘤学杂志, 2018, 45(2): 103-106.

CHEN Luo-Jun, TIAN Jing-Yuan, LI Na, SONG Qi-Bin. Roles of platelets in tumor progression[J]. Journal of International Oncology, 2018, 45(2): 103-106.

参考文献

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