乳腺癌保乳或改良根治术后内乳淋巴结照射的研究进展

doi:10.3760/cma.j.issn.1673-422X.2020.03.009

摘要/Abstract

摘要：

随着时代的发展,乳腺癌保乳或改良根治术加放疗的综合治疗技术更加趋于成熟和完善。内乳淋巴结作为乳腺淋巴引流的第一站一直倍受关注。目前,对于内乳淋巴结的照射与否存有争议。已有研究表明包含内乳淋巴结的局部区域淋巴结照射有生存获益价值,然而内乳淋巴结照射作为区域淋巴结照射的一部分也被证明会导致心、肺毒性增加,因而部分研究机构及学者对内乳淋巴结照射仍持怀疑态度。近年来,随着放疗技术和设备的改进以及临床经验的积累,越来越多的学者倾向于行内乳淋巴结放疗。但是需要重视内乳淋巴结照射适应证,以选择适当的治疗方案,使患者达到真正的治疗获益。

关键词: 乳腺肿瘤, 内乳区淋巴结, 放射疗法

Abstract:

With the development of the times, the comprehensive treatment technology of breast conserving or modified radical mastectomy plus radiotherapy for breast cancer has become more mature and perfect. As the first station of lymphatic drainage of breast, internal mammary lymph nodes have been paid much attention. At present, there is a controversy about whether the internal mammary lymph nodes are irradiated or not. Previous studies have shown that local lymph nodes irradiation containing internal mammary lymph nodes has survival benefit value. However, as a part of regional lymph nodse irradiation, internal mammary lymph nodes irradiation has also been proved to increase the toxicity of heart and lung, which leads to some research institutions and scholars to remain skeptical about internal mammary lymph nodes irradiation. In recent years, with the improvement of radiotherapy technology and equipment and the accumulation of clinical experience, more and more scholars tend to accept internal mammary lymph nodes radiotherapy. But we should pay attention to the indications of internal mammary lymph nodes irradiation, in order to select appropriate treatment options to achieve real benefits.

Key words: Breast neoplasms, Internal mammary lymph node, Radiotherapy

彭彩云, 韩春, 王澜. 乳腺癌保乳或改良根治术后内乳淋巴结照射的研究进展[J]. 国际肿瘤学杂志, 2020, 47(3): 174-179.

Peng Caiyun, Han Chun, Wang Lan. Advances in radiation of internal mammary lymph nodes after breast-conserving or modified radical surgery for breast cancer[J]. Journal of International Oncology, 2020, 47(3): 174-179.

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