国际肿瘤学杂志 ›› 2019, Vol. 46 ›› Issue (8): 492-495.doi: 10.3760/cma.j.issn.1673-422X.2019.08.010

• 综述 • 上一篇    下一篇

血液学炎症标志物在鼻咽癌中的临床应用价值

周媛媛  李旌   

  1. 广西壮族自治区柳州市人民医院肿瘤放疗科  545006
  • 收稿日期:2019-04-28 修回日期:2019-05-09 出版日期:2019-08-08 发布日期:2019-10-31
  • 通讯作者: 周媛媛 E-mail:zyy00mail@sina.com
  • 基金资助:

    广西壮族自治区卫生和计划生育委员会自筹经费科研课题(Z20170707)

Clinical practice value of hematological inflammation biomarkers in nasopharyngeal carcinoma

Zhou Yuanyuan, Li Jing   

  1. Department of Radiation Therapy, Liuzhou General Hospital, Guangxi Zhuang Autonomous Region, Liuzhou 545006, China
  • Received:2019-04-28 Revised:2019-05-09 Online:2019-08-08 Published:2019-10-31
  • Contact: Zhou Yuanyuan E-mail:zyy00mail@sina.com
  • Supported by:

    Self-financing Scientific Research of Health and Family Planning Commission of Guangxi Zhuang Autonomous Region (Z20170707)

摘要: 炎症可促进肿瘤的发生、发展、浸润、转移。鼻咽癌中血液学炎症标志物异常(外周血中性粒细胞淋巴细胞比值、血小板淋巴细胞比值、全身免疫炎症指数、C反应蛋白等)是炎症在肿瘤发展中的临床表现,通过对鼻咽癌患者中的血液学炎症标志物检测可获得提示预后的信息,对现有的预后指标起到补充作用,有助于指导个体化临床治疗策略的制定,为临床实践提供更多的思路。

关键词: 鼻咽肿瘤, 预后, 血液学炎症标志物

Abstract: Inflammation promotes tumor initiate, progress, invade and metastasize. Hematological inflammation biomarkers in nasopharyngeal carcinoma (peripheral blood neurtrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, systemic immune-inflammation index and C-creative protein) are the expressions of inflammation in the progress of nasopharyngeal carcinoma. The information of prognosis can be obtained by testing the hematological inflammation biomarkers in nasopharyngeal carcinoma patients. These biomarkers are the supplement for the current prognosis predictive indices and they can be used to guide the clinical practice, which will provide more ideas.

Key words: Nasopharyngeal neoplasms, Prognosis, Hematological inflammation biomarker