国际肿瘤学杂志 ›› 2019, Vol. 46 ›› Issue (7): 439-442.doi: 10.3760/cma.j.issn.1673-422X.2019.07.011

• 综述 • 上一篇    下一篇

晚期胃癌的维持治疗

姚杨,贾英杰,邓仁芬,李小江,孔凡铭   

  1. 天津中医药大学第一附属医院肿瘤科300193
  • 出版日期:2019-07-08 发布日期:2019-07-16
  • 通讯作者: 孔凡铭 E-mail:kongfanming08@163.com
  • 基金资助:

    天津市卫生和计划生育委员会中医药重点领域科研课题(2017003);天津市科技计划(17ZXMFSY00190);天津市卫生计生行业高层次人才选拔培养工程

Maintenance treatment for advanced gastric cancer

Yao Yang, Jia Yingjie, Deng Renfen, Li Xiaojiang, Kong Fanming   

  1. Department of Oncology, First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
  • Online:2019-07-08 Published:2019-07-16
  • Contact: Kong Fanming E-mail:kongfanming08@163.com
  • Supported by:

    Research Project in Key Areas of Traditional Chinese Medicine of Tianjin Health and Family Planning Commission (2017003); Science and Technology Plan of Tianjin of China (17ZXMFSY00190); Tianjin Health and Family Planning Industry Highlevel Talent Selection and Training Project

摘要: 目前替吉奥和卡培他滨是晚期胃癌较为理想的维持治疗药物;在运用免疫及靶向药物维持治疗晚期胃癌的临床试验中,伊匹单抗未能取得阳性结果,雷莫芦单抗尚未取得研究数据,曲妥珠单抗、贝伐珠单抗及阿维单抗的维持治疗试验方案都显示出了初步的有效性;中医药疗法在维持治疗中显示出一定的有效性,仍需进一步研究。

关键词: 胃肿瘤, 药物疗法, 维持治疗

Abstract: S-1 and capecitabine are relatively ideal agents for maintenance treatment of advanced gastric cancer. In clinical trials of using immune and targeted drugs for maintenance treatment of advanced gastric cancer, ipilimumab fails to obtain positive results, ramucirumab has not obtained research data, and trial regimens of maintenance treatment with trastuzumab, bevacizumab and avelumab have all shown initial efficacy. Traditional Chinese medicine therapy has shown some effectiveness in maintenance treatment, which still needs further researches.

Key words: Stomach neoplasms, Drug therapy, Maintenance treatment