胃癌预后相关lncRNA分子标志物的研究进展

doi:10.3760/cma.j.issn.1673-422X.2019.07.010

摘要/Abstract

摘要： 基因测序方面的研究发现，长非编码RNA（lncRNA）虽不编码蛋白质，但参与胃癌某些生物学通路，在胃癌预后及转归等过程中发挥着一定的作用。随着基因数据库的产生及计算机算法的普及，胃癌预后相关lncRNA的研究逐渐增多。胃癌预后lncRNA的生物信息学研究可为实验研究提供思路，以探索得到更多与胃癌预后相关的lncRNA，以期为胃癌诊治及改善预后提供参考价值。

关键词: 胃肿瘤, 预后, RNA, 长链非编码

Abstract: Researches on gene sequencing find that long non-coding RNA (lncRNA) does not encode protein, however, it participates in the biological pathway of gastric cancer and plays a certain role in the process of prognosis and outcome of gastric cancer. With the generation of gene databases and the popularity of computer algorithms, the researches on the prognosis-related lncRNA of gastric cancer are gradually increasing. The bioinformatics study of prognosisrelated lncRNA of gastric cancer can provide ideas for experimental researches. It is expected to provide evidence for the diagnosis and treatment of gastric cancer and improve prognosis by exploring more lncRNAs that are related to the prognosis of gastric cancer.

Key words: Stomach neoplasms, Prognosis, RNA, long noncoding

刘辉，常紫薇，张秋萌，张超，景丽伟. 胃癌预后相关lncRNA分子标志物的研究进展[J]. 国际肿瘤学杂志, 2019, 46(7): 434-438.

Liu Hui, Chang Ziwei, Zhang Qiumeng, Zhang Chao, Jing Liwei. Research progress of prognosis-related lncRNA molecular markers in gastric cancer[J]. Journal of International Oncology, 2019, 46(7): 434-438.

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