国际肿瘤学杂志

国际肿瘤学杂志 ›› 2019, Vol. 46 ›› Issue (2): 91-93.doi: 10.3760/cma.j.issn.1673-422X.2019.02.006

• 综述 • 上一篇    下一篇

肿瘤相关代谢对肿瘤免疫的影响

 杨茜露, 黄云超   

  1. 昆明医科大学第三附属医院（云南省肿瘤医院）胸外一科 云南省肺癌重点实验室650118
  • 出版日期:2019-02-08 发布日期:2019-04-03
  • 通讯作者: 黄云超，Email: huangych2001@aliyun.com E-mail:huangych2001@aliyun.com
  • 基金资助:

    国家自然科学基金（81702274）

Effect of tumor metabolism on tumor immunity

Yang Qianlu, Huang Yunchao   

  1. Department of First Chest Surgery, Third Affiliated Hospital of Kunming Medical University (Yunnan Provincial Cancer Hospital), Key Laboratory of Lung Cancer of Yunnan Province, Kunming 650118, China
  • Online:2019-02-08 Published:2019-04-03
  • Contact: Huang Yunchao, Email: huangych2001@aliyun.com E-mail:huangych2001@aliyun.com
  • Supported by:

    National Natural Science Fundation of China (81702274)

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摘要： 肿瘤相关代谢与肿瘤的发生、发展及肿瘤免疫逃逸的行为密切相关。肿瘤代谢（如葡萄糖代谢、氨基酸代谢、氧代谢）的局部营养物质消耗及代谢产物对免疫细胞的影响是肿瘤免疫研究领域的热点，可用于指导与肿瘤免疫相关的抗肿瘤药物开发。

关键词: 肿瘤, 免疫, 细胞, 代谢

Abstract: Tumor metabolism is closely related to tumor occurrence, development and the behavior of tumor immune escape. The local nutrient consumption (such as glucose metabolism, amino acid metabolism and oxygen metabolism) of tumor metabolism and the effect of metabolites on immune cells are the hotspots in the field of tumor immunology and it can also guide the research of new anticancer drugs related to tumor immunity.

Key words: Neoplasms, Immunity, cellular, Metabolism