国际肿瘤学杂志

国际肿瘤学杂志 ›› 2017, Vol. 44 ›› Issue (5): 397-400.doi: 10.3760/cma.j.issn.1673422X.2017.05.019

• 综述 • 上一篇    

肝癌干细胞表面标志物研究进展

保靖夫   

  1. 210093 南京大学医学院临床医学部
  • 出版日期:2017-05-08 发布日期:2017-04-19
  • 通讯作者: 保靖夫，Email: eclipse1992611@163.com E-mail:eclipse1992611@163.com

Research progress on surface markers of liver cancer stem cells

Bao Jingfu   

  1. Department of Clinical Medicine, Medical School of Nanjing University, Nanjing 210093, China
  • Online:2017-05-08 Published:2017-04-19
  • Contact: Bao Jingfu E-mail:eclipse1992611@163.com

PDF

598

摘要： 近年来研究发现，表达CD133、CD90、上皮细胞黏附分子、CD13、趋化因子受体4、CD44及ATP结合盒蛋白转运体的肝癌细胞在肝癌的生长、复发和转移中发挥重要作用。肝癌干细胞由众多不同表型的细胞构成，上述细胞均可能是肝癌干细胞的重要组成部分，这为肝癌干细胞理论的进一步发展及实际应用带来了困难。

关键词: 肝肿瘤, 肿瘤干细胞, 抗原, 表面

Abstract: Recent studies find that cancer cells which express CD133, CD90, epithelial cell adhesion molecule, CD13, chemokine receptor 4, CD44 and ATPbinding cassette transporters play important roles on growth, recurrence and metastasis of liver cancer. Liver cancer stem cells constitute by cells which have different phenotype. Mentioned above cells may be important parts of liver cancer stem cells, which bring difficulties for the further development and practical application of theory about liver cancer stem cells.【Key words】Liver neoplasms; Neoplastic stem cells; Antigens, surface