国际肿瘤学杂志 ›› 2015, Vol. 42 ›› Issue (7): 525-528.doi: 10.3760/cma.j.issn.1673-422X.2015.07.013

• 综述 • 上一篇    下一篇

组织因子阳性膜微粒及其在肿瘤中的作用和检测

李会桥,张予辉   

  1. 100020 首都医科大学附属北京朝阳医院呼吸科
  • 出版日期:2015-07-08 发布日期:2015-05-26
  • 通讯作者: 张予辉 E-mail:zhangyhcy@163.com
  • 基金资助:

    第47批教育部留学回国人员科研启动基金(320.6750.12623)

Roles and detection of tissue factor positive microparticle in tumor

Li Huiqiao, ZhangYuhui   

  1.  Department of Respiration, Beijing Chaoyang Hospital Affiliated to Capital University of Medical Science, Beijing 100020, China
  • Online:2015-07-08 Published:2015-05-26
  • Contact: ZhangYuhui E-mail:zhangyhcy@163.com

摘要: 组织因子阳性膜微粒(TFMP)通过促进肿瘤周围血管生成,进而促进肿瘤浸润和转移。目前多项研究提示TFMP与肿瘤合并血栓形成具有相关性,但相关机制尚不完全清楚。研究TFMP对肿瘤进展及血栓的预测极其重要。

关键词: 肿瘤, 静脉血栓形成, 凝血致活酶, 膜微粒

Abstract: Tissue factor positive microparticle (TFMP) plays an important role in the invasion and metastasis of tumor by promoting the formation of the vessels around the tumor. At present a number of studies suggest that TFMP is associated with thrombosis in tumor, but the relevant mechanism is still not fully clear. TFMP is extremely important for the prevention of tumor progression and thrombosis.

Key words: Neoplasms, Venous thrombosis, Thromboplastin, Microparticle