国际肿瘤学杂志 ›› 2015, Vol. 42 ›› Issue (10): 756-758.doi: 10.3760/cma.j.issn.1673-422X.2015.10.010

• 综述 • 上一篇    下一篇

肿瘤的分子诊断与靶向治疗概述

郑晓文,王玉平,周永宁   

  1. 730000 兰州大学第一医院消化内科 甘肃省胃肠病重点实验室
  • 出版日期:2015-10-08 发布日期:2015-09-08
  • 通讯作者: 周永宁 E-mail:yongningzhou@sina.com

Overview of molecular diagnosis and targeted treatment of tumor

Zheng Xiaowen, Wang Yuping, Zhou Yongning   

  1. Department of Gastroenterology, First Hospital of Lanzhou University; Key Laboratory for Gastrointestinal Diseases of Gansu Province, Lanzhou 730000, China
  • Online:2015-10-08 Published:2015-09-08
  • Contact: Zhou Yongning E-mail:yongningzhou@sina.com

摘要: 肿瘤的发生和转归与基因的参与有关,通过实时PCR技术检测体内某些基因的表达可以早期诊断肿瘤及判断患者的预后。通过对异常基因和分子的分析,设计和研制出具有针对性的靶向药物,从而达到“稳、准、狠”的治疗效果,减少不良反应,提高生命质量。

关键词: 肿瘤, 分子诊断技术, 靶向治疗

Abstract: The occurrence and outcome of cancer is related to the involved gene; Detecting the expression of gene in body by the realtime PCR technology can diagnose and evaluate the prognosis of patients early. Through analyzing the abnormal genes and molecular, designing and studying the targeted drugs can achieve the therapeutic effect of "steady, accurate, relentless", at the same time to reduce side effects and to improve the quality of life.

Key words: Neoplasms, Molecular diagnostic techniques, Targeted treatment