国际肿瘤学杂志

国际肿瘤学杂志 ›› 2014, Vol. 41 ›› Issue (7): 523-525.doi: 10.3760/cma.j.issn.1673422X.2014.07.013

• 综述 • 上一篇    下一篇

肝癌动物模型研究进展

 黄佳飞, 周洪渊, 张倜   

  1. 300060 天津医科大学附属肿瘤医院肝胆科
  • 出版日期:2014-08-04 发布日期:2014-08-04
  • 通讯作者: 张倜，Email:zhangti@tjmuch.com E-mail:zhangti@tjmuch.com
  • 基金资助:

    天津市自然科学基金（11JCZDJC18800）；国家自然科学基金（81372635）

Progress in research on animal models of liver cancer

 HUANG  Jia-Fei, ZHOU  Hong-Yuan, ZHANG  Ti   

  1. Department of Hepatobiliary, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China
  • Online:2014-08-04 Published:2014-08-04
  • Contact: Zhang Ti E-mail:zhangti@tjmuch.com

PDF

1611

被引次数

13

摘要： 肝癌动物模型的建立具有重要价值。动物模型的建立分为实验动物的选择和肿瘤的来源两部分。因肿瘤的来源不同又可以将模型分为不同的类型，不同类型的模型具有各自相应的特点和局限性。理想的肝癌动物模型应该在生物学习性、生化性质、病理学特征等方面与人类肝癌相类似，并且模型制作过程简便易行。

关键词: 肝肿瘤, 模型, 动物

Abstract: As a result, establishing animal models of liver cancer is of high value. There are two parts of the establishment of animal models—the selection of laboratory animals and the source of tumors.  The animal models could be classified into different patterns due to difference sources of tumor, and these different patterns possess distinctive characters and limitations. The ideally animal models should satisfy the general requirements of biological habits, biochemical properties, and pathological features which are similar with human hepatocellular and  easy to establish.

Key words: Liver neoplasms, Models, animal