国际肿瘤学杂志 ›› 2014, Vol. 41 ›› Issue (11): 854-857.doi: 10.3760/cma.j.issn.1673-422X.2014.11.017

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骨转移癌微环境与治疗靶点

  

  1. 200233上海交通大学附属第六人民医院骨科
  • 出版日期:2014-12-03 发布日期:2015-01-20
  • 通讯作者: 杨庆诚,Email:tjyqc@163.com

Microenvironment and therapeutic targets of metastatic bone cancer

  1.  Department of Orthopeadics,the Sixth People′s Hospital,Shanghai Jiaotong University,Shanghai 200233,China
  • Online:2014-12-03 Published:2015-01-20
  • Contact: Yang Qingcheng, Email: tjyqc@163.com

摘要: 目前骨转移癌的治疗手段相当有限,且疗效不显著。骨转移癌靶向治疗研究是当前的热点,同时也是难点。对骨微环境中成骨细胞、破骨细胞及肿瘤细胞等相互关系的最新研究成果,可为临床上治疗骨转移癌提供新的思路和方法。

关键词: 肿瘤转移, 骨组织, 靶向治疗

Abstract: Microenvironment and therapeutic targets of metastatic bone cancerYang Jielai, Yang Qingcheng.Corresponding author:【Abstract】Currently, the treatment of bone metastases is quite limited,and the effect is not significant.It is a tempting but difficult task to find valid therapy.The recent research on bone microenvironment, including the osteoblasts, osteoclasts and tumor cells et al,may provide new targets and methods for the treatment of bone metastases.

Key words: Neoplasm metastasis, Bone tissue, Targeted therapy