国际肿瘤学杂志 ›› 2014, Vol. 41 ›› Issue (10): 750-753.doi: 10.3760/cma.j.issn.1673422X.2014.10.010

• 综述 • 上一篇    下一篇

miR-21与头颈部恶性肿瘤

蒋烈浩,葛明华,凌志强   

  1. 325035温州医学院第一临床医学院(蒋烈浩);浙江省
    肿瘤医院头颈肿瘤外科(蒋烈浩、葛明华);浙江省肿瘤医院 浙江省肿
    瘤研究所(蒋烈浩、凌志强)
  • 出版日期:2014-10-29 发布日期:2014-10-11
  • 通讯作者: 葛明华,Email:gemingh@163.com E-mail:gemingh@163.com
  • 基金资助:

    浙江省卫生高层次创新人才培养工程基金[浙卫发
    (2008)134号];卫生部科学研究基金浙江省医药卫生重大科技计划
    (WKJ20122021);浙江省医药卫生平台重点资助计划(2012ZDA005)

miR21 and head and neck carcinoma

 JIANG  Lie-Hao, GE  Ming-Hua, LING  Zhi-Qiang   

  1. First School of Clinical Medicine, Wenzhou Medical College, Wenzhou 325035, China; Department of Head and Neck Surgical Oncology, Zhejiang Cancer Research Institute, Zhejiang Province Cancer Hospital, Hangzhou 310022, China
  • Online:2014-10-29 Published:2014-10-11
  • Contact: GeMinghua E-mail:gemingh@163.com

摘要:  近年来研究发现 miR21在多种头颈部恶性肿瘤中存在异常表达,该异常表达与甲状腺 癌、鼻咽癌、喉癌和口腔癌等头颈部恶性肿瘤的发生发展都存在密切的联系,并且可能对头颈部恶性肿 瘤的术前诊断、临床治疗及预后的判断具有重要的价值。

关键词: 微 RNAs, 治疗, 预后

Abstract: In recent years, the abnormal expression of microRNA21 (miR21) in head and neck carcinoma have been found in many studies, which may be closely related to the genesis and development of thyroid carcinoma, nasopharyngeal carcinoma, laryngocarcinoma and oral carcinoma, etc. MiR21 may also be valuable for the clinical diagnosis, treatment and prognosis of head and neck carcinoma.

Key words: MicroRNAs, Therapy, Prognosis